Cutting-edge research introduced synthetic proteins designed via generative AI that outperform natural genome-editing proteins, enhancing precision and efficiency in gene editing. Complementing this, scientists at the Spanish National Cancer Research Centre released the comprehensive 'human REPAIRome', cataloging DNA double-strand break repair patterns linked to nearly 20,000 human genes. These resources deepen understanding of genome maintenance and open pathways for refined gene therapies and personalized cancer treatments.