Researchers adapted a previously developed gene‑drive strategy to a local Tanzanian mosquito strain and tested an antiparasitic transgene (MM‑CP) expressing magainin‑2 and melittin in a secure facility. Published work in Nature showed the modification reduced Plasmodium falciparum oocyst growth and sporozoite output in genetically diverse parasite isolates, and delayed migration to salivary glands. The study advances gene‑drive evaluation beyond lab strains toward ecologically relevant contexts, but authors emphasize containment, regulatory oversight and extensive field‑level risk assessment before any release consideration.