Pacific Biosciences and EpiCypher have entered a comarketing agreement for the Cutana Hia5 methyltransferase enzyme, a key reagent in the Fiber-seq assay. Fiber-seq leverages enzymatic DNA methylation patterns combined with PacBio’s HiFi sequencing to provide simultaneous insights into chromatin accessibility, DNA methylation, and genetic variation at the single-molecule level. EpiCypher also launched Fiber-seq assay services to early-access customers, expanding multiomics capabilities for understanding gene regulation and rare diseases.