Researchers reported a stabilized MERS‑CoV spike protein presented on a ferritin nanoparticle induced robust immune responses in preclinical studies. The stabilized spike nanoparticle vaccine enhanced neutralizing titers and durability compared with non‑stabilized constructs. The approach mirrors nanoparticle strategies used in other coronavirus vaccines and could accelerate preparedness for MERS outbreaks. Vaccine developers seeking broadly deployable coronavirus platforms may view stabilizing spike antigens on self‑assembling scaffolds as a high‑value design path.