Researchers are developing an Eye-in-a-Care-Box (ECaBox) perfusion device that maintains freshly removed eyeballs to reduce degeneration outside the body. The approach aims to preserve the eye’s structure and apparent functional capacity long enough to make eye transplantation more feasible. In experiments reported using pig eyes, untreated eyes deteriorated within 24 hours even with cooling, while perfused eyes showed significantly higher viability. Additional tests suggested preserved eyes could respond to light, indicating the device may help maintain the physiological signaling needed for vision after transplantation. Industry relevance: eye transplant viability depends heavily on post-excision preservation, so perfusion-based preservation platforms could become enabling infrastructure for emerging ophthalmic transplant workflows. Key industry takeaway: ECaBox perfusion extends eye viability after donor removal in animal testing.