Two international research efforts, including the University of Washington-led 1KGP-LRS Consortium and collaborators from PacBio and Johns Hopkins University, have advanced long-read sequencing of the 1000 Genomes Project samples. By integrating data from both Oxford Nanopore and PacBio platforms, they are mapping structural variants and isoform diversity with high resolution across diverse populations. These expanded datasets fill gaps in previous human genome assemblies, particularly in complex regions such as centromeres and segmental duplications. Public release of this deeper sequencing data is expected to accelerate genomic research and precision medicine.