A University of South Florida team reported a potential pathway to preserve heart function in Duchenne muscular dystrophy, with results published in Molecular Therapy. The study focused on cardiac decline, a major driver of morbidity in DMD patients, and identified an approach aimed at maintaining cardiopulmonary performance as disease progresses. For DMD stakeholders, the work adds a candidate heart-protection strategy beyond muscle-focused readouts, reinforcing the need for therapies that address cardiac outcomes early rather than treating them as late-stage complications.