Sophia Genetics launched Sophia DDM Digital Twins, an AI‑powered research module that builds patient-specific computational replicas using multimodal clinical, imaging and genomic datasets to simulate treatment responses and disease trajectories. The company framed Digital Twins as a research-use tool to accelerate translational oncology work and to help match patients to trials. Separately Broad Clinical Labs, collaborating with Roche and Boston Children’s, reported an ultra‑rapid whole‑genome sequencing workflow using Roche’s SBX Sequencing‑by‑Expansion platform that reduced sample‑to‑result times to roughly four hours in neonatal critical‑care cases. Together these developments highlight accelerated adoption of AI and faster sequencing technologies in precision oncology and acute care pathways, while raising questions about clinical validation, regulatory pathways and operational deployment.