DeepMind publishes AlphaGenome—AI models the regulatory 'dark genome'

DeepMind released AlphaGenome (also reported as Alphagenome), an AI system designed to predict the functional effects of noncoding regulatory variants across long DNA sequences. The model reportedly handles sequences up to one million base pairs and predicts multiple molecular properties—such as gene expression, splicing, and DNA accessibility—at scale. DeepMind frames AlphaGenome as a tool for prioritizing regulatory variants from genome-wide studies and for identifying therapeutic targets; researchers note applications in rare‑variant interpretation and synthetic regulatory design.