A team led by Liu, Y., Xu JS, and Cao L. developed a CRISPR‑based assay to detect BK virus and JC virus infections in kidney transplant recipients. The assay targets viral nucleic acids with CRISPR‑mediated readout, offering rapid, sensitive surveillance for two polyomaviruses that threaten graft function in immunocompromised patients. Authors propose the test as a point‑of‑care tool to guide early antiviral or immunosuppression adjustments.