A CRISPR-based diagnostic developed by Liu, Xu, and Cao rapidly detects BK and JC viruses in post-kidney-transplant patients, improving surveillance timelines for polyomavirus reactivation. The assay targets viral sequences with CRISPR-mediated cleavage and readout, offering a faster molecular alternative to standard PCR workflows. Investigators tested the platform in clinical samples and reported high sensitivity and specificity versus conventional methods. The team highlights potential for decentralized monitoring of immunocompromised patients where timely detection can guide immunosuppression adjustments to prevent graft loss.