Corvus Pharmaceuticals reported early clinical data showing robust activity for oral ITK inhibitor soquelitinib in atopic dermatitis, prompting a sharp market rally. The company said the latest cohort demonstrated deepening responses over eight weeks, including activity in patients previously treated with systemic therapies. Soquelitinib targets IL‑2‑inducible T‑cell kinase (ITK), a mechanism being explored for inflammatory and immune disease indications. Corvus presented cohort data from an ongoing randomized, placebo‑controlled phase I study; management will move the program into mid‑stage testing based on these results. Investors interpreted the readout as evidence the molecule could compete with injectable biologics in efficacy and convenience.
Get the Daily Brief