A new Cochrane evidence and gap map found a striking imbalance in dengue prevention research: hundreds of primary studies exist, but the evidence most needed by health authorities remains difficult to find or interpret. The work consolidates the global landscape and highlights where trial outcomes and study quality may not be meeting decision-making needs. The map is positioned as a tool for directing future research toward the questions most relevant to public health deployment—such as prevention strategies that can be evaluated consistently and compared across settings. For biotech and vaccine developers, the findings underline the importance of generating evidence that translates into actionable policy rather than just increasing the number of studies. The report also provides a structured view of what is already covered versus where uncertainties persist, which can influence how sponsors design next-stage efficacy and implementation studies.