The U.S. Centers for Disease Control and Prevention announced it will end its longstanding guidance that all newborns should receive the hepatitis B vaccine, marking a substantial change in national immunization policy. The agency’s updated guidance and the rationale behind the shift were released publicly, prompting immediate discussion among clinicians, public‑health advocates, and pediatric societies. The change will affect hospital birthing policies, neonatal care protocols, and vaccine counseling practices. Stakeholders cited in media briefings noted implementation will require updates to electronic health records, newborn order sets, and provider education to ensure appropriate risk‑based vaccination decisions at birth.