Cutting-edge spatial omics and proteomic platforms are advancing biomarker discovery and disease characterization. The GeoMx Discovery Proteome Atlas offers high-plex protein profiling with over 1200 targets, enabling detailed tissue-level insights. Giotto Suite software integrates multiomics spatial data for comprehensive molecular analyses. Tools like Syncell’s Microscoop enable unbiased single-cell proteome mapping with subcellular resolution. These technologies facilitate deep understanding of tumor microenvironments and cellular interactions essential for precision medicine.