Innovative cancer treatments show promise across multiple fronts. A peptide-based vaccine inducing immune responses against lymph node-resident cancer cells demonstrates encouraging results in pancreatic cancer patients, potentially preventing relapse. Separately, a newly discovered small molecule, d-cysteine, inhibits cysteine desulfurase NFS1, stalling tumor growth through metabolic disruption. Additionally, advances include the development of antitumor mRNA vaccines for personalized gastric cancer treatment and multi-epitope nanoparticles enhancing tumor targeting for immunotherapy.