Recent studies have further elucidated the molecular underpinnings of Alzheimer’s disease and neurodegeneration. Weill Cornell researchers demonstrated that a rare APOE3 Christchurch gene mutation delays Alzheimer’s by suppressing inflammatory signaling via the cGAS-STING pathway in brain immune cells. This highlights inflammation as a prime therapeutic target. Separately, a novel closed-loop electrical stimulation system was shown to halt epilepsy progression and preserve memory by delivering targeted pulses in response to neural activity markers. Additionally, advances in digitized language analysis using NLP offer promising tools for early detection and monitoring of Parkinson’s disease by identifying subtle linguistic biomarkers.