Cutting-edge AI tools are accelerating the design and application of gene editing technologies. Profluent's OpenCRISPR-1, an AI-generated programmable gene editor, demonstrates superior editing activity, specificity, and lowered immunogenicity compared to natural counterparts, enabling scalable therapeutic development. Meanwhile, the CRISPR-GPT system integrates large language models with domain expertise to guide gene editing experiment design, democratizing access for users across skill levels. Additionally, an interdisciplinary AI 'Virtual Lab' simulates collaborative research for complex biomedical questions, demonstrating AI's expanding role in biotechnology research and personalized medicine innovation.