Maria Jasin, PhD, recognized for pioneering research revealing how homologous recombination repairs DNA breaks and suppresses cancer development, won the 2025 Pearl Meister Greengard Prize. Her work elucidated the role of BRCA1 and BRCA2 in maintaining genome integrity and gene editing foundations, profoundly influencing cancer biology and therapy. Jasin’s research continues to shape understanding of DNA repair mechanisms and cancer prevention strategies.