Multiple studies unveiled novel molecular targets and mechanisms offering hope in combating lethal cancers. Indiana University researchers identified two proteins critical to pancreatic cancer's resistance to treatment, proposing combination drug strategies. Salk Institute and UC San Diego reported that boosting a sugar molecule on cell surfaces slows pancreatic tumor progression and metastasis. Separately, glioblastoma research revealed the role of fetal oncogenes and cell plasticity, providing avenues for innovative therapies against treatment-resistant brain tumors.