Novel research highlights promising therapeutic strategies across oncology and neurology. Identification of autoantibodies influencing immunotherapy response offers a route to improved cancer treatment. Advances in Alzheimer's showed reversal of cognitive decline with a combination of existing anticancer drugs in a mouse model. Glioblastoma research and immune escape mechanisms in various cancers continue to reveal targets for intervention. Meanwhile, neurodevelopmental disorder treatment progresses with prime editing gene therapy correcting mutations in vivo, underscoring gene editing’s clinical promise.