10x Genomics and Curio Bioscience said they reached an agreement in principle to resolve their spatial biology patent infringement litigation, prompting cancellation of a scheduled jury trial. The case involved patents licensed by 10x from Prognosys Biosciences and covered aspects of spatial biology workflows. The parties filed a joint motion with the court to vacate pending deadlines after agreeing to voluntarily resolve the dispute, with terms not disclosed publicly. 10x previously sued Curio for alleged infringement and has also targeted other platform makers in related patent fights. For the spatialomics ecosystem, the settlement reduces near-term legal uncertainty around platform design and procurement while leaving questions about how quickly competitors may adjust documentation and workflows to reduce exposure.