Researchers at the University of Illinois Urbana-Champaign have developed oPool+ display, a scalable platform integrating oligonucleotide pool synthesis and mRNA display to synthesize and characterize hundreds of antibodies in parallel. This method compresses weeks or months of experimental characterization into mere days, enabling large-scale screening of antibody binding specificities across diverse antigens. The technology promises to expedite antibody drug discovery by unlocking comprehensive insights into antibody diversity and specificity at unprecedented speed and scale.