Basecamp Research reported that its EDEN family of evolutionary AI models can design programmable gene‑insertion tools that place large therapeutic DNA sequences at precise genomic sites. In preprint data, EDEN designed inserts at over 10,000 disease‑related loci and produced engineered T cells that cleared >90% of tumor cells in lab assays. The preprint team included collaborators from Nvidia and Microsoft; the work relies on BaseData, a massive proprietary genomics corpus assembled from diverse global samples. Basecamp also secured investment from NVentures. The achievement expands on CRISPR‑era editing by addressing larger payload insertion challenges, a technical barrier for many gene‑replacement and cell‑engineering programs. Who’s involved: Basecamp Research, Nvidia, NVentures; results shared in a preprint and investor disclosures. The findings are early and not yet peer‑reviewed, but they mark a notable step in AI‑driven therapeutic design.
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