Researchers led by Professor Hiroaki Suzuki at Chuo University have pioneered a microfluidic-based technology for mass-producing uniform artificial cells containing DNA condensates simulating natural nuclei. Their method utilizes osmotic pressure modulation within lipid bilayer vesicles to achieve spontaneous and controlled DNA condensation, circumventing harsher chemical or heat-based approaches that can compromise biological activity. This breakthrough facilitates synthetic biology applications by enabling scalable production of artificial cells with the potential to mimic complex cellular functions and protein synthesis, advancing bottom-up construction of cell-like systems.