ARPA‑H awarded UC San Diego a $25.77 million, 60‑month grant to develop patient‑specific, 3D‑bioprinted human livers under the PRINT program. The multidisciplinary team will combine rapid high‑resolution bioprinting, patient‑derived cells and AI‑designed vascular networks to scale functional liver tissue as a transplant alternative. UC San Diego framed the effort as an attempt to remove dependence on donor organs and lifelong immunosuppression by producing immunocompetent, personalized grafts. The project is positioned as a long‑term translational program with multiple engineering and regulatory inflection points ahead.