The Advanced Research Projects Agency for Health (ARPA‑H) awarded UC San Diego up to $25,771,771 to develop patient‑specific, 3D bioprinted human livers under the agency’s PRINT program. The five‑year project aims to fabricate transplantable livers from a patient’s own cells and to integrate AI‑designed vascular networks and immunocompetent features, UC San Diego said. The grant supports a multidisciplinary team and rapid‑printing technology the lab has developed, with explicit goals to address organ shortages and reduce the need for lifelong immunosuppression. Clarification for readers: 3D bioprinting here refers to layer‑by‑layer deposition of cells and biomaterials to recreate organ microarchitecture and vascularization, a technical bottleneck the team plans to solve using AI and novel biomanufacturing workflows.
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