Nature Biotechnology published a study showing that a self‑assembling host‑defense peptide mimic forms micelles that codeliver antifungal drugs, producing potent combinatorial activity and lower toxicity. The micelle platform enhanced drug efficacy against invasive fungal models while mitigating host toxicity signals. The work presents a delivery‑driven therapeutic strategy to revive or boost existing antifungals and offers a translational path for combination regimens in life‑threatening mycoses. For clinicians and preclinical teams, the paper provides pharmacologic and formulation data that could inform IND‑enabling studies.