Nature Biotechnology and related work report converging advances in antifungal delivery using self-assembling peptide micelles. One study shows a host-defense peptide mimic that self-assembles into delivery micelles to co-deliver antifungal agents, achieving potent combinatorial activity and lower systemic toxicity in preclinical models. An independent team engineered peptide micelles that enhance drug accumulation and antifungal potency while reducing off-target effects. Both efforts prioritize delivery platforms that enable combination therapy against invasive fungal pathogens, a clinically urgent area given rising resistance.