A Nature Biotechnology paper reports a self‑assembling host‑defense peptide mimic that forms antifungal micelles to co‑deliver drugs and boost efficacy. The study showed that codelivery within micelles produced superior antifungal activity and reduced systemic toxicity in preclinical models compared with conventional formulations. Authors demonstrated combinatorial benefits against resistant fungal strains and argued the platform could revive existing antifungal agents whose therapeutic windows are limited by toxicity. The paper includes pharmacokinetic and efficacy readouts that support further preclinical development.