Cadence Molecular Sciences has launched ROCS X, an AI-enabled virtual screening platform capable of conducting three-dimensional searches across trillions of drug-like molecules. Developed in collaboration with Treeline Biosciences, ROCS X integrates phase-stabilized spectral stitching technology with AI-driven shape and electrostatic overlays, achieving performance improvements of over 1,000-fold compared to conventional methods. Treeline reports identification of over 150 novel drug candidates using ROCS X, underscoring its potential to accelerate and diversify early-stage drug discovery significantly.