Researchers have demonstrated a brain-computer interface that decodes neural signals to generate synthesized speech with paralinguistic features such as tone and melody in real time. Implanted with 256 electrodes, a man with severe dysarthria due to amyotrophic lateral sclerosis communicated intelligibly and expressively, achieving near-instantaneous voice synthesis with closed-loop auditory feedback. This marks a technological leap beyond previous BCIs that produced text or delayed speech outputs, opening possibilities for restoring naturalistic communication in paralysis.