Artificial intelligence continues to revolutionize biological and clinical research. Novel deep learning models accurately predict microsatellite instability-high tumors’ response to immune checkpoint inhibitors. AI accelerates protein engineering and designs custom binders, addressing elusive targets like intrinsically disordered proteins. In clinical care, AI-driven prediction models forecast pediatric acute kidney injury risk and ultrasound wireless charging innovations for implantable devices. These advancements promise to streamline diagnostics, enhance therapeutic design, and optimize patient outcomes across biomedical sectors.