Researchers at the University of Illinois Urbana-Champaign engineered a novel solid-state nanopore platform using 2D materials, advancing label-free single-biomolecule detection technology. Published in PNAS, this platform addresses longstanding fabrication challenges and offers scalable, wafer-compatible manufacturing potential. It aims to enable high-resolution DNA sequencing with solid-state devices, overcoming limitations of biological nanopores and positioning the technology for precision medicine applications.