Leading cancer centers showcased novel radiation oncology technologies to improve treatment precision and outcomes. UCLA Health highlighted targeted radioactive therapy approaches for recurrent prostate cancer, advanced stereotactic body radiation techniques, and 5DCT-guided imaging innovations. The University of Cincinnati Cancer Center presented breakthroughs across head and neck, hepatocellular carcinoma, and other malignancies. Sylvester Comprehensive Cancer Center from the University of Miami will also present pivotal findings. These developments contribute to precision oncology and personalized radiotherapy.