10x Genomics filed two patent lawsuits against Illumina alleging infringement tied to sequencing and single-cell/spatial technologies as it seeks to broaden its product portfolio. The complaints, filed in Delaware federal court, accuse the sequencing giant of using patented methods central to 10x’s single-cell and spatial transcriptomics offerings. The litigation escalates a long-running IP battle that has accompanied the rapid commercialization of single-cell and spatial tools. Legal outcomes could reshape competitive positioning and licensing dynamics across a high-growth diagnostics and discovery market.