10x Genomics launched a next‑generation Chromium Flex assay designed to scale single‑cell experiments to high sample and cell numbers: up to 384 samples and the capacity to profile up to 100 million cells per week in a 96‑well plate format compatible with automation. The next‑gen Flex emphasizes cost efficiency and plate‑based multiplexing for large discovery and translational programs. The company said the assay retains Flex chemistry sensitivity while enabling automation‑compatible workflows to reduce reagent waste and support high‑throughput studies such as CRISPR screens and FFPE translational cohorts. Early access customers, including the Allen Institute, described the assay as transformative for large‑scale immunology and functional genomics efforts. 10x positions the update as a response to growing demand for high‑quality biological datasets to feed AI and multiomics pipelines, lowering barriers for studies that previously relied on bulk methods.